Products related to Discovery:
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Knowledge Guided Machine Learning : Accelerating Discovery using Scientific Knowledge and Data
Given their tremendous success in commercial applications, machine learning (ML) models are increasingly being considered as alternatives to science-based models in many disciplines.Yet, these "black-box" ML models have found limited success due to their inability to work well in the presence of limited training data and generalize to unseen scenarios.As a result, there is a growing interest in the scientific community on creating a new generation of methods that integrate scientific knowledge in ML frameworks.This emerging field, called scientific knowledge-guided ML (KGML), seeks a distinct departure from existing "data-only" or "scientific knowledge-only" methods to use knowledge and data at an equal footing.Indeed, KGML involves diverse scientific and ML communities, where researchers and practitioners from various backgrounds and application domains are continually adding richness to the problem formulations and research methods in this emerging field.Knowledge Guided Machine Learning: Accelerating Discovery using Scientific Knowledge and Data provides an introduction to this rapidly growing field by discussing some of the common themes of research in KGML using illustrative examples, case studies, and reviews from diverse application domains and research communities as book chapters by leading researchers.KEY FEATURES First-of-its-kind book in an emerging area of research that is gaining widespread attention in the scientific and data science fields Accessible to a broad audience in data science and scientific and engineering fields Provides a coherent organizational structure to the problem formulations and research methods in the emerging field of KGML using illustrative examples from diverse application domains Contains chapters by leading researchers, which illustrate the cutting-edge research trends, opportunities, and challenges in KGML research from multiple perspectives Enables cross-pollination of KGML problem formulations and research methods across disciplines Highlights critical gaps that require further investigation by the broader community of researchers and practitioners to realize the full potential of KGML
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Knowledge Discovery from Archaeological Materials
This Element highlights the employment within archaeology of classification methods developed in the field of chemometrics, artificial intelligence, and Bayesian statistics.These operate in both high- and low-dimensional environments and often have better results than traditional methods.The basic principles and main methods are introduced with recommendations for when to use them.
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Anticandidal Therapeutics : Discovery and Development
Developments of antifungal agents have declined as compared to other antibiotics that have displayed a potent development with time.There is an urgent need for both prophylactic and therapeutic treatments worldwide to control the severity of infections caused by Candida.Anticandidal Therapeutics: Discovery and Development provides the readers with a compiled knowledge of the fungal human infection Candida and the development of anticandidal drugs.Anticandidal Therapeutics helps researchers form the basis for the discovery and development of novel anticandidal therapies.In 14 chapters this book provides collective information on anticandidal agents and their discovery and development with respect to major drug transporter families, different stages of anticandidal agent development, recent trends and progress in antifungal translational research, clinical studies status of anticandidal therapeutic agents, and drug repurposing for development of novel anticandidal agents.
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Web-Scale Discovery Services : Principles, Applications, Discovery Tools and Development Hypotheses
Web-Scale Discovery Services: Principles, Applications, Discovery Tools and Development Hypotheses summarizes and presents the state-of-the-art in WSDS.The title promotes a middle-way between finding the best tool for each particular need and the search for the most reliable systems.The title identifies basic theoretical problems and offers practical solutions for librarians.The volume offers a summary of ideas from around the world, giving a new perspective that is backed up by strong theory.Offering a vision for libraries, this book also allows archivists, museum specialists, computer scientists, commercial operators and interested users to deepen their culture and information literacy. The great number of information sources now available and the changing habits of web users has led to the development of Web Scale Discovery Services (WSDS).The goal of these systems and techniques is to make catalogues, databases, institutional repositories, Open Access archives and other databases searchable and discoverable through a single point of access.The diffusion of systems and connections between data disseminated by libraries and published by other institutions poses a challenge to understanding discovery in the modern library.
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Do you need prior knowledge for Star Trek: Discovery?
No, prior knowledge of the Star Trek universe is not necessary to enjoy Star Trek: Discovery. The show is designed to be accessible to both new viewers and longtime fans of the franchise. While there are references and connections to the larger Star Trek universe, the show's storylines and characters are introduced in a way that allows new viewers to easily follow along and become immersed in the world of Star Trek.
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What is an old discovery?
An old discovery refers to a scientific or historical finding that was made a significant amount of time ago. These discoveries have often stood the test of time and have had a lasting impact on our understanding of the world. Examples of old discoveries include the theory of evolution by Charles Darwin, the discovery of electricity by Benjamin Franklin, and the invention of the printing press by Johannes Gutenberg. These discoveries have shaped our modern world and continue to be studied and celebrated for their significance.
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What was Luther's great discovery?
Luther's great discovery was the concept of justification by faith alone. He believed that individuals could be saved by their faith in God alone, rather than through good works or the sacraments of the Catholic Church. This idea challenged the traditional teachings of the Church and sparked the Protestant Reformation. Luther's emphasis on faith as the key to salvation had a profound impact on Christianity and led to the formation of new Protestant denominations.
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Series like Star Trek: Discovery
Series like Star Trek: Discovery are typically science fiction shows that explore themes of space exploration, advanced technology, and diverse alien cultures. They often feature a diverse cast of characters and focus on moral and ethical dilemmas faced by the crew. These series also tend to have high production values, intricate storylines, and a mix of action and drama. Fans of Star Trek: Discovery may enjoy other similar shows like The Expanse, Battlestar Galactica, and Doctor Who.
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On Learning, Volume 3 : Knowledge, Curriculum and Ethics
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On Learning, Volume 3 : Knowledge, Curriculum and Ethics
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Neglected Tropical Diseases : Drug Discovery and Development
A drug discovery reference to the crippling tropical diseases that affect more than 1 billion people. Neglected Tropical Diseases is the first book of its kind to offer a guide that follows the World Health Organization?s list of neglected tropical diseases.The authors?all are experts on the topic?address the development of effective treatments for 12 crippling infectious diseases that affect almost 20% of the world?s popluation. The book includes information on the common approaches and the most important factors that lead to the development of new drugs for treating tropical diseases.Individual chapters review 12 neglected tropical diseases that are grouped by infectious agent, from viruses to bacteria to eukaryotic parasites.For each of these diseases, the book explains the unmet medical need and explores the current and potential drug discovery strategies.The book also includes information on potential drug compounds derived from natural products.This important book: -Ties together information from different sources for developing novel treatsments forneglected tropical diseases -Is aligned with WHO?s initiative to eradicate tropical diseases -Outlines current and potential drugs for treating tropical diseases -Provides a standard reference for the entire field Written for medicinal chemists, pharmaceutical chemists, pharmaceutical industry, virologists, parasitologists, and specialists on tropics medicine, Neglected Tropical Diseases offers an essential guide and a systematic reference for the development of successful treatments for 12 crippling infectious diseases.
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Basic Principles of Drug Discovery and Development
Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields.Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator’s fields.This book bridges the knowledge gaps that invariably lead to communication issues in a new scientist’s early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development.It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process.The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process.
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What is your latest discovery?
My latest discovery is a new method for synthesizing a novel class of organic compounds with potential applications in drug development. By using a combination of computational modeling and organic synthesis techniques, my team and I were able to design and create these compounds with improved properties compared to existing ones. This discovery has the potential to open up new avenues for the development of more effective and targeted medications for various diseases.
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What was the gold discovery?
The gold discovery refers to the event in 1848 when gold was discovered at Sutter's Mill in California, sparking the California Gold Rush. The discovery led to a massive influx of people from all over the world seeking their fortunes in gold mining. This event had a significant impact on the development of California and the United States, as it led to rapid population growth and economic prosperity in the region.
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What kind of discovery is this?
This discovery is a significant scientific breakthrough in the field of astronomy. The detection of a new exoplanet, especially one that is potentially habitable, is a rare and exciting find. It opens up new possibilities for studying the potential for life beyond our solar system and deepens our understanding of the universe.
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What is the discovery of radioactivity?
The discovery of radioactivity is the phenomenon where certain elements spontaneously emit radiation in the form of particles or electromagnetic waves. This was first observed by Henri Becquerel in 1896 when he noticed that uranium salts emitted rays that could expose photographic plates. This discovery led to further research by Marie and Pierre Curie, who identified the elements polonium and radium as being radioactive. Radioactivity has since been found to have important applications in medicine, industry, and energy production.
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