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Cheminformatics, QSAR and Machine Learning Applications for Novel Drug Development
Cheminformatics, QSAR and Machine Learning Applications for Novel Drug Development aims at showcasing different structure-based, ligand-based, and machine learning tools currently used in drug design.It also highlights special topics of computational drug design together with the available tools and databases.The integrated presentation of chemometrics, cheminformatics, and machine learning methods under is one of the strengths of the book.The first part of the content is devoted to establishing the foundations of the area.Here recent trends in computational modeling of drugs are presented.Other topics present in this part include QSAR in medicinal chemistry, structure-based methods, chemoinformatics and chemometric approaches, and machine learning methods in drug design.The second part focuses on methods and case studies including molecular descriptors, molecular similarity, structure-based based screening, homology modeling in protein structure predictions, molecular docking, stability of drug receptor interactions, deep learning and support vector machine in drug design.The third part of the book is dedicated to special topics, including dedicated chapters on topics ranging from de design of green pharmaceuticals to computational toxicology.The final part is dedicated to present the available tools and databases, including QSAR databases, free tools and databases in ligand and structure-based drug design, and machine learning resources for drug design.The final chapters discuss different web servers used for identification of various drug candidates.
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On Learning, Volume 3 : Knowledge, Curriculum and Ethics
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On Learning, Volume 3 : Knowledge, Curriculum and Ethics
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School : A Novel
Both an exorcism of contemporary academia and a comedic portrait of an artist seeking the means to survive At once angry and jubilant, Ray Levy’s School is a curse on life in a dying university system and an incantation for transforming the material of one’s academic humbling into a vessel for capacious, creative selfhood. The novel incorporates a variety of forms, including a dissertation manuscript possessed by the spirit of Marquis de Sade, a lecture on psychoanalysis delivered as stand-up comedy by a dysphoric graduate student, a review of a found-footage horror movie that’s also a YouTube video of a conference presentation on French theory, an interview with an avant-garde filmmaker that’s really an invocation for conjuring your demon brother, and more.The whole functions as a caustic ritual. School overshares and withholds, cites and dÉtournÉs, chants and channels as it invokes the dead fathers of deconstruction for the black mass that occurs painfully and parodically across the pages. A hand-biting tale, one that chews off the finger instead of kissing the ring, School is a deeply unprofessional book about intellectual professions with reference to endless debt and neoliberalization, coercive seduction rites and fetishizations of authority, and the realization of a life in which you have not lost—and, yes, you deserve the full horizon of possibility.
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Crime novel or detective novel?
A crime novel typically focuses on the criminal act and its consequences, often from the perspective of the perpetrator, victim, or both. On the other hand, a detective novel centers around the investigation of a crime, usually by a professional or amateur detective. While both genres often overlap, the primary difference lies in the focus of the story – crime novels delve into the motivations and actions of the criminal, while detective novels revolve around the process of solving the crime.
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Is the novel Tannoed now a crime novel or a social novel?
"Tannoed" can be considered both a crime novel and a social novel. While the story revolves around a murder investigation and the unraveling of dark secrets, it also delves into the social issues and tensions within the community. The novel explores themes of power dynamics, corruption, and the impact of societal expectations on individuals. Ultimately, "Tannoed" blends elements of both genres to create a complex and multifaceted narrative.
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Is the novel Tannoed now a detective novel or a social novel?
The novel "Tannoed" can be considered both a detective novel and a social novel. While it follows the protagonist's investigation into a crime, it also delves into social issues such as corruption, power dynamics, and societal inequalities. The novel intertwines elements of both genres to create a complex and multi-layered narrative that explores both the mystery at hand and the broader social context in which it unfolds.
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Which youth novel is suitable for school?
One youth novel that is suitable for school is "The Giver" by Lois Lowry. This novel is often included in school curriculums because it addresses important themes such as individuality, conformity, and the consequences of a controlled society. The language and content are appropriate for young readers, and the thought-provoking story can lead to meaningful discussions in the classroom. Additionally, the novel has won numerous awards and is considered a modern classic in youth literature.
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School Days : A Novel
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Knowledge and the Future School : Curriculum and Social Justice
Written at a time of uncertainty about the implications of the English government’s curriculum policies, Knowledge and the Future School engages with the debate between the government and large sections of the educational community.It provides a forward-looking framework for head teachers, their staff and those involved in training teachers to use when developing the curriculum of individual schools in the context of a national curriculum.While explaining recent ideas in the sociology of educational knowledge, the authors draw on Michael Young’s earlier research with Johan Muller to distinguish three models of the curriculum in terms of their assumptions about knowledge, referred to in this book as Future 1, Future 2 and Future 3.They link Future 3 to the idea of 'powerful knowledge' for all pupils as a curriculum principle for any school, arguing that the question of knowledge is intimately linked to the issue of social justice and that access to 'powerful knowledge' is a necessary component of the education of all pupils.Knowledge and the Future School offers a new way of thinking about the problems that head teachers, their staff and curriculum designers face.In charting a course for schools that goes beyond current debates, it also provides a perspective that policy makers should not avoid.
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The Knowledge Seeker : A Young-Adult Dystopian Novel
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Learning to Speak Southern : A Novel
A searing Southern story about confronting the difference between the family you're born into and the family you choose, from the acclaimed author of How to Bury Your BrotherLex fled Memphis years ago, making ends meet with odd jobs teaching English around the world.She only returns when she has no choice, when her godmother presents her with a bargain she can't refuse.Lex has never understood her mother, who died tragically right before Lex's college graduation, but now she's got a chance to read her journals, to try and figure out what sent her mother spiraling all those years ago. The Memphis that Lex inhabits is more bourbon and bbq joint than sweet tea on front porches, and as she pieces together the Memphis her mother knew, seeing the lure of the world through her mother's lush writing, she must confront more of her own past and the people she left behind.Once all is laid bare, Lex must decide for herself: What is the true meaning of family?
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How can I rewrite this graphic novel into a novel?
To rewrite a graphic novel into a novel, you can start by focusing on the dialogue and narration. Describe the visual elements and actions in detail, using vivid language to bring the scenes to life. You can also expand on the characters' thoughts and emotions to provide deeper insight into their motivations and experiences. Additionally, consider adding more descriptive passages to set the scene and create a rich, immersive world for the reader. Finally, ensure that the plot and pacing are well-developed and engaging, allowing for a smooth transition from the visual format to the written word.
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What is the difference between web novel and light novel?
The main difference between web novels and light novels lies in their publication and distribution. Web novels are typically published online on websites or platforms, often by amateur writers and are available for free. Light novels, on the other hand, are published in print and are often written by professional authors. Light novels also tend to have illustrations, making them more visually appealing, while web novels may not have illustrations. Additionally, light novels are often targeted towards a specific audience, such as young adults, and are usually part of a series with a consistent publishing schedule.
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Search for a novel or crime novel about marital drama.
"Gone Girl" by Gillian Flynn is a gripping crime novel that delves into the complexities of a marriage. The story follows the disappearance of Amy Dunne and the subsequent investigation into her husband, Nick, as the prime suspect. As the plot unfolds, the novel explores the dark and twisted dynamics of their relationship, revealing secrets and lies that keep the reader on the edge of their seat. The book is a thrilling exploration of marital drama and the lengths people will go to in order to maintain their facade of a perfect marriage.
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Which young adult novel is suitable for school?
One young adult novel that is suitable for school is "The Hate U Give" by Angie Thomas. This novel addresses important themes such as racism, police brutality, and social justice, making it a relevant and thought-provoking choice for students. It has been widely praised for its powerful storytelling and engaging characters, making it a great option for sparking discussions and promoting empathy and understanding among students. Additionally, the novel's accessible language and compelling narrative make it a suitable choice for a wide range of readers in a school setting.
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